PEP/NEWS — Peptide intel. Daily.

Elad Gil is CEO of Gil & Co, a multi-stage investment firm, holding company, and operating company working on the world’s most advanced technologies. Elad is a serial entrepreneur, operating executive, and investor or advisor to private com

I used to weigh 300 pounds. I tried every restrictive diet, became a vegan, and trained 90 minutes a day for 18 months with absolute zero results. Everything changed when I drank a cup of yak butter tea at 18,300 feet in Tibet. Within 30 se

Scientists recorded kisspeptin (a reproductive signaling peptide) neuron activity in live mice across the full estrous cycle. The data shows a prolonged surge pattern that directly triggers the LH spike needed for ovulation.

Aging disrupts the gut's immune surveillance, making it easier for harmful bacteria to take hold. New research in Aging Cell maps exactly how that breakdown unfolds at the mucosal level.

A new study found creatine added measurable benefit on top of power training in older adults. The effect was additive — not just parallel — which matters for anyone designing a resistance-plus-supplementation protocol.

T cells may hold onto a pro-inflammatory state for years after normal weight is restored following obesity. The finding raises real questions about GLP-1 weight-loss wins — metabolic repair and immune repair may not happen on the same timeline.

Bryan Johnson outlines 14 home modifications aimed at cutting exposure to particulates, microplastics, and chemical residues. Some cost nothing — others require more investment. Useful as a checklist for the environmentally aware optimizer.

Dr. Junyue Cao's lab built an ultra-high-throughput single-cell map of how the body ages at the cellular level. His Science paper offers one of the most detailed aging atlases to date — and points to cell types that lead the decline.