PEP/NEWS — Peptide intel. Daily.

In this Huberman Lab Essentials episode, I explain the biology and psychology of obsessive-compulsive disorder (OCD) and describe the neural circuitry behind repetitive "thought-action loops," including why compulsive actions actually stren

Are morning erections becoming less frequent or disappearing altogether? It may be more than just aging. In this video, we explain the science behind morning erections (morning wood) and why they're one of the simplest indicators of your v

In May, I got diagnosed with autoimmune gastritis (AIG). We are going to try and cure it. 🥦 Start your Blueprint protocol: https://blueprint.bryanjohnson.com/?&utm_source=youtube&utm_medium=video&utm_content= 📩 Get my protocol updates: h

Use code DELAUER20 for 20% off Rho Nutrition's Liposomal NAD: https://rhonutrition.com/discount/Delauer20?redirect=/products/liposomal-nad This video does contain a paid partnership with a brand that helps to support this channel. It is be

Peter Attia reviews the latest data on GLP-1 receptor agonists (drugs like semaglutide used for weight loss) and lean mass retention. His takeaway: adequate protein and resistance training largely offset muscle loss risk.

Centenarians carrying certain SIRT6 gene variants accumulate fewer senescent cells. The finding helps rank which aging mechanisms most deserve therapeutic attention.

A new network-based approach predicts which approved drugs may extend lifespan by matching them to known aging hallmarks. It offers a faster path to longevity candidates without starting from scratch.

Restricting food to an 8-hour window extended median lifespan in male mice by 12%. Researchers note the effect may partly reflect voluntary caloric reduction — but the signal is real.

Animal data suggests microbiome composition influences muscle and brain aging at least as much as diet or exercise. Restoring a younger microbial balance in aged animals reverses some of that decline.

Bryan Johnson outlines the four cardiovascular protocols behind his vascular-age results. The piece focuses on lifestyle and measurement frameworks — not supplements.

A new review shows that senescent cells degrade stem cell populations across tissue types. Mouse studies continue to show rapid rejuvenation when senescent cells are selectively cleared.

Researchers found a primate-specific non-coding RNA that amplifies cellular senescence. The discovery is notable because it may explain why some aging findings in rodents don't translate cleanly to humans.

New research maps the molecular links between age-related muscle loss (sarcopenia) and bone loss (osteoporosis). The two conditions reinforce each other through shared signaling pathways — which means treating one may help the other.

Part two of Research Vials' cancer biology series covers how tumors spread and which peptides show up in the early literature. It maps the mechanisms researchers are targeting — without making therapeutic claims.

The third installment takes on the harder questions: does GH secretagogue use carry cancer risk, what does the washout data show, and where does the evidence actually land? A grounded read for anyone tracking GH-axis peptides.