PEP/NEWS — Peptide intel. Daily.

In this video, Dr. Rena Malik breaks down what the latest research says about omega-3s and erectile dysfunction. Learn why fish oil may not improve erections, what this new study found, and why your overall diet, heart health, exercise, sle

Use code THOMAS at puori.com/THOMAS to get 32% off your first Puori Grass-fed Whey Protein order when you start a subscription! This video does contain a paid partnership with a brand that helps to support this channel. It is because of br

New research proposes that inflammation starts in peripheral tissues — not the brain — and reaches the brain via extracellular vesicles in the bloodstream. If confirmed in humans, it could shift early intervention targets for Parkinson's disease.

Part one of a three-part series lays out the cell biology behind tumor formation. It explains which signaling pathways cancers exploit — foundational context for the peptide-specific risk and benefit data covered in parts two and three.

The final part of the series addresses the question researchers most want answered: do GH secretagogues (a class of peptides that raise growth hormone) carry meaningful cancer risk? It covers current evidence, washout considerations, and where the data is still thin.

Researchers found that how fast an individual's epigenetic age is changing matters as much as where it sits at any single time point. Accelerating biological age — not just elevated biological age — is the stronger mortality signal.

Scientists tied disrupted calcium ion balance to accelerated aging in both progeroid and naturally aging mice. Correcting it with a repurposed antidepressant produced significant lifespan gains. The mechanism now warrants investigation in longer-lived species.

Johnson outlines the cardiovascular interventions behind his claim of vascular age equivalent to a late teenager. The protocols focus on blood pressure, VO2 max, and inflammation markers — with specific lifestyle levers for each.

A new Nature Aging perspective places TERT — the enzyme that extends telomeres — at the top of the aging pathway hierarchy. It argues that TERT activity affects far more than telomere length, touching mitochondrial function and inflammation as well.

Researchers show that aging hematopoietic stem cells accumulate an inflammatory memory — a process called trained immunity. That memory then drives the systemic low-grade inflammation common in older adults.

Scientists built a spatial map of senescent microglia (immune cells that can become inflammatory with age) in white matter of aging mouse brains. They then tested senolytic drugs — compounds that clear senescent cells — and found localized clearance.

Rats bred for high aerobic fitness showed a different epigenetic signature in the aging brain compared to low-capacity counterparts. The data add to evidence that VO2 max training has neuroprotective effects that go beyond blood flow.