PEP/NEWS — Peptide intel. Daily.

Join Thrive Market today and get $20 off your first three orders plus a free $60 gift! http://thrivemarket.com/Thomas This video does contain a paid partnership with a brand that helps to support this channel. It is because of brands like

Delicious Electrolytes: https://store.nuvisionhealthcenter.com/collections/electrolyte I Lost 20Lbs Immediately When I Stopped Eating These 6 Foods is a video highlighting how to get rid of visceral fat quickly. Visceral fat is silently de

271: In this episode, I'm sitting down with anesthetist and physician assistant Sandra Bargeron to explore an often-overlooked aspect of surgery: protecting your brain. Did you know that anesthesia is a neurological stress test of your brai

In this video, Dr. Rena Malik breaks down what the latest research says about omega-3s and erectile dysfunction. Learn why fish oil may not improve erections, what this new study found, and why your overall diet, heart health, exercise, sle

A new method using exosomes from mesenchymal stem cells (MSCs) reduced harmful metabolic changes in mouse livers. Exosome-based delivery is gaining traction as a way to get therapeutic signals into tissue without using whole cells.

Combining a senolytic vaccine with mesenchymal stem cells produced a synergistic effect in mice with acute, artificially induced injury. Researchers caution that the findings need replication in more naturalistic aging models before conclusions hold.

In his 400th episode AMA, Peter Attia maps the real-world environmental threats to longevity — air pollution, noise, light exposure, and EMFs — and lays out practical mitigation strategies. His framing: optimize the environment without making daily life unlivable.

Swedish preventive health platform Neko Health closed a $700 million Series C led by Lightspeed, valuing it at $1.8 billion. The company is expanding into the US and growing its longitudinal health dataset and proprietary diagnostic tools.

Disrupting the CDK4/6–RARα–NF-κB signaling axis reduced the chronic inflammation driven by senescent cells in both aging mice and post-chemotherapy models. This pathway could become a drug target for senescence-associated inflammation without full senolytic clearance.

A new Nature Aging analysis places TERT — the catalytic subunit of telomerase — at the top of a regulatory hierarchy governing cellular aging. The argument positions TERT not just as a telomere-maintenance enzyme but as a broader coordinator of aging biology.

A new study proposes that aging or Parkinson's-linked mutations generate inflammation in peripheral tissues first. Circulating extracellular vesicles then carry that inflammatory signal to the brain — a route that could reframe early intervention targets.

Research found that mitochondria from raw plants can survive digestion, enter the bloodstream, reach cells, and interact with native mitochondria in ways that improve function. It is a surprising data point for dietary research and a potential angle for mitochondrial therapy.

Attia's AMA on GLP-1 receptor agonists (the drug class behind semaglutide and tirzepatide) and lean mass finds that with proper protein intake and resistance training, muscle loss is minimal. The episode brings new data to one of the most contested questions in metabolic medicine.

True cellular therapeutics require stem cells that can survive and repair from within inflamed, ischemic, or age-degraded tissue. This piece explores the engineering approaches being used to build more resilient therapeutic cells.

Dubai has established a formal longevity authority, and AEON is among the organizations positioning around it. The move could shift where next-generation therapies — including peptide-based approaches — get developed and first deployed.

Researchers used spatial mapping to identify senescent and disease-associated microglia in aged mouse brain white matter, then targeted them with senolytics. The work offers a more precise model for brain-specific senolytic intervention.

A Nature Aging study connects blood stem cell aging to trained immunity — a form of immune memory that drives age-associated chronic inflammation. The finding adds mechanistic detail to inflammaging research.