PEP/NEWS — Peptide intel. Daily.

Could erectile dysfunction be an early warning sign of something happening in your blood vessels? In this video, Dr. Rena Malik breaks down new research linking two lesser-known blood markers to erectile dysfunction and explains why erectio

Dr. Fei-Fei Li, PhD, is a professor of computer science at Stanford University and a pioneer and expert in artificial intelligence (AI). We discuss how AI can be used safely and effectively to extend human capabilities – not just to search

Discover why a simple compound from tree pulp might outshine most modern prescription drugs for chronic pain and cellular repair. If you like this, please like, share, and subscribe! Follow The Spartan everywhere: Instagram: https://www.

Blocking RANKL — a protein that drives bone breakdown — prevented bone loss, improved muscle function, and extended lifespan in mice with accelerated aging. The findings raise questions about RANKL as a dual target in normal aging research.

The current CEO of Human Longevity Inc. makes the case that health optimization requires individuals to take ownership of their own data. He draws on hard lessons from the company's turbulent early years.

Methylation-based epigenetic clocks can give wildly different readings when short-term biological stress — illness, intense exercise, poor sleep — occurs near the sampling window. That matters a lot for anyone using clocks to judge whether a peptide or longevity intervention is working.

Kate Tolo used multispectral imaging to track eight skin markers over time. The data-guided approach reversed her measured skin age by nearly three decades.

Switching on GPR81 — a receptor normally triggered by lactate during exercise — reduced signs of cellular senescence and improved muscle performance in progeroid cell models. The finding adds a new angle to exercise-mimetic research.

Blocking SLC25A1 — a mitochondrial transporter — cuts the inflammatory signals that senescent cells pump out. It doesn't clear the cells, but it quiets the damage they do, opening a complementary lane to senolytics.

The plant compound diosgenin pushed satellite cells — the stem cells that repair muscle — back into an active growth state. It worked through the SIRT1/PGC-1α pathway, which overlaps with targets studied in peptide-mediated muscle research.

Andrew Huberman sat down with Tim Ferriss to cover peptides, performance optimization, and his full protocol framework. It's one of the most candid public conversations Huberman has had on the peptide research landscape.

Stem-cell-derived exosomes reduced inflammation and fibrosis in heart tissue after a simulated heart attack. The heart regenerates poorly on its own — this line of research aims to change that without full cell transplantation.

The third installment of this series tackles GH secretagogues (compounds that trigger growth hormone release) and the cancer-risk question directly. It maps where the evidence is strong, where it's thin, and what a washout period looks like in research contexts.

Before you can understand how peptides interact with cancer biology, you need to understand how cancer starts. This foundation piece maps the key pathways tumors exploit — and where peptide mechanisms intersect.

Lifespan.io's monthly digest covers research progress across senolytics, epigenetic reprogramming, and longevity policy. July included at least one outcome the editors describe as a 'horrifying failure.'

This week's Fight Aging! newsletter covers approaches to rejuvenate aging blood stem cells, the bile acid–gut microbiome aging connection, and a sweep of the latest longevity research.

Fight Aging! makes the structural argument: as longevity interventions proven in animals move toward the clinic, the field stops being a niche and starts reshaping mainstream medicine from the inside.