PEP/NEWS — Peptide intel. Daily.

Dr. Ralph Adolphs, PhD, is a Professor of Psychology, Neuroscience, and Biology at Caltech and a leading expert on the science of human emotions. We discuss how emotions shape our attention and decision-making, whether emotions are truly “s

Insilico Medicine's Virtual Aging Cell platform treats biological age as a core variable — not an afterthought. The multi-agent AI system models cellular change across six scales, from molecules to populations, aiming to simulate aging and test interventions computationally.

AgelessRx secured a $1 million milestone award from the $101 million XPRIZE Healthspan competition. The platform delivers personalized aging care via telehealth — one of ten finalists still in the running for the top prize.

Peter Attia's Episode 404 features psychiatrist Linus Abrams, who argues that hormone signaling — not just neurotransmitters — drives mental health outcomes. The conversation covers psychedelic therapies and why reducing symptoms falls short of restoring full human function.

Bryan Johnson's Blueprint team breaks down the difference between true low-level laser therapy (LLLT) and LED devices often sold as equivalent. The American Hair Loss Association recognizes LLLT as the gold standard for light-based hair regrowth — and the distinction has real clinical weight.

Cutting dietary valine — one of the three branched-chain amino acids — extended median and maximum lifespan in male mice by 23%. Both sexes showed improved healthspan. The finding adds to growing evidence that amino acid composition, not just calorie count, shapes longevity.

Part 3 of Research Vials' peptide-cancer series addresses growth hormone secretagogues specifically — including what the risk literature actually says and where washout periods fit into responsible research design. Straight-line signal without the marketing overlay.

Fight Aging! reviews new evidence on why senescent cell accumulation accelerates with age. The short answer: the immune system loses its ability to clear them. That single failure may drive a cascade of inflammation and tissue damage across multiple organ systems.

Attia's latest written piece tackles the limits of multifactorial clinical trials — studies that test many interventions at once. He argues the difference between what these trials can prove and what they can't matters far more than it appears in the headlines.

People with myasthenia gravis — a rare autoimmune condition affecting neuromuscular junctions — outlive the general population by roughly five years on average. Fight Aging! examines the leading hypotheses and what the survival advantage might reveal about immune regulation and longevity.

Blocking the RANKL protein pathway in mice with accelerated aging prevented bone loss, improved muscle function, and extended lifespan. The finding adds to evidence that the bone-muscle axis is a meaningful longevity target, not just a structural concern.

Animal studies suggest senolytic therapies — drugs that clear senescent cells — can slow or reverse progression of idiopathic pulmonary fibrosis. Fight Aging! reviews the mechanism and what stands between current animal data and a usable human therapy.